Once you have done this, click the "apply" tab then "ok", you will be asked to restart your computer, do so. What you have just done is prevent programs from starting when your computer does, this will not stop all spyware but it will make your computer run faster in aid of the other steps you need to take.
The next step towards purifying your PC is to get spyware removal software, the two that I would recommend are SpyBot S&D, and Ad-aware SE Personal Edition - both are free and easy to use, SpyBot also comes with a handy "immunise" feature that helps protect against spyware from getting to your computer in the first place. It is reccomended that you use more than one spyware protection program, as they vary in the types of spyware that they can detect and remove. The final step in basic spyware protection is to employ the service of a firewall, this will restrict and prevent the downloading of further spyware to your system.
The software I would recommend for this is "Outpost Firewall", it is very simplistic yet rather effective - and comes with a 30 day free trial. When you have taken these steps, and restarted your computer - you should notice that it runs much faster than before, if it doesn't then the problem may lie with hardware, or a virus.
